Researchers at MIT have developed a new purification method using selective crystallization to greatly improve the purity and yield of viral vector-based gene therapy drugs. This innovative process reduces the operating time for purification from nearly 40 hours to just four hours, potentially cutting the cost of gene therapy drugs by five to ten times. The method exploits slight differences in the electrical potential between active viruses and empty capsids, a breakthrough for the large-scale production of medicine.
Source: MIT News
Link: https://news.mit.edu/2025/new-method-could-improve-manufacturing-gene-therapy-drugs-1028






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